Fig. 1 · Structure
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NDM-1-IN-6
NDM-1 Inhibitor
NDM-1-IN-6 is a selective and competitive inhibitor of New Delhi Metallo-β-lactamase-1 (NDM-1), exhibiting a Ki of 0.72 μM. It demonstrates a synergistic antibacterial effect when combined with the carbapenem antibiotic Meropenem, making it a valuable tool for studying NDM-1-mediated multidrug-resistant bacterial infections. This compound is primarily utilized in research applications aimed at understanding and combating antibiotic resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 80570-90-7 |
| Applications | NDM-1 Inhibitor |
| Formula | C11H11N3OS |
| Molecular Weight | 233.29 |
| SMILES | OC1=CC=CC=C1C2=NN=C(N2CC=C)S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.