Fig. 1 · Structure
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Necroptosis-IN-1
Necroptosis Inhibitor
Necroptosis-IN-1 is a potent inhibitor of necroptosis, primarily targeting receptor-interacting protein kinase (RIPK). This compound effectively hinders necroptotic cell death pathways, making it a valuable tool for research involving cell death mechanisms. Its application spans studies related to inflammation, neurodegeneration, and cancer, providing insights into the role of necroptosis in various pathological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1391980-92-9 |
| Applications | Necroptosis Inhibitor |
| Formula | C12H10ClN3O2 |
| Molecular Weight | 263.68 |
| SMILES | O=C1NC(C(CC2=CNC3=C2C=CC=C3Cl)N1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.