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Ned 19 is a selective membrane-permeant non competitive NAADP antagonist and inhibits NAADP-mediated Ca2+ signaling, with an IC50 of 65 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.43 mL | 97.16 mL | 194.33 mL |
| 0.5 mM | 3.89 mL | 19.43 mL | 38.87 mL |
| 1 mM | 1.94 mL | 9.72 mL | 19.43 mL |
| 5 mM | 0.39 mL | 1.94 mL | 3.89 mL |
*The above data is based on the productmolecular weight 514.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21597 |
|---|---|
| Actions | Antagonist |
| CAS No. | 874374-25-1 |
| Formula | C30H31FN4O3 |
| M. Wt | 514.59 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | Ned19, Ned-19 |
| SMILES | OC(C(C1)NC(C2=CC=C(OC)C(CN3CCN(C4=CC=CC=C4F)CC3)=C2)C5=C1C6=C(N5)C=CC=C6)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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