NEK7 degrader-2 (Compound 25) is a targeted NEK7 degrader that facilitates dose-dependent degradation of NEK7 specifically in human PBMC-derived macrophages. This compound effectively reduces the release of pro-inflammatory cytokine IL-1β triggered by NLRP3 inflammasome activation. NEK7 degrader-2 serves as a valuable tool for investigating the mechanisms underlying inflammatory diseases.
NEK7 degrader-2 (Compound 25) is a targeted NEK7 degrader that facilitates dose-dependent degradation of NEK7 specifically in human PBMC-derived macrophages. This compound effectively reduces the release of pro-inflammatory cytokine IL-1β triggered by NLRP3 inflammasome activation. NEK7 degrader-2 serves as a valuable tool for investigating the mechanisms underlying inflammatory diseases.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
