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Form	MW
Nemazoline hydrochloride This page	280.58
Nemazoline	244.12

Nemazoline hydrochloride

Nasal Decongestant

Nemazoline hydrochloride is a selective α-adrenergic agent that functions primarily as a nasal decongestant. It exerts its biological activity by inducing α1-mediated contraction of capacitance vessels, effectively alleviating nasal congestion without significantly compromising blood flow due to its α2-antagonist properties. Additionally, Nemazoline hydrochloride counteracts endogenous noradrenaline-induced α2 constriction of resistance vessels, making it a valuable tool for research into vascular dynamics and respiratory conditions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	111073-18-8
Applications	Nasal Decongestant
Formula	C₁₀H₁₂Cl₃N₃
Molecular Weight	280.58
Synonyms	A-57219; SCH 40054
SMILES	ClC1=C(N)C(Cl)=CC(CC2=NCCN2)=C1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.