|Discription||Netupitant is a selective neurokinin 1 (NK1) receptor antagonist. It competitively binds to and blocks the activity of the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV).|
Store lyophilized at -20ºC, keep desiccated.
|In vitro||DMSO||2 mg/mL (3.45 mM)|
|Ethanol||85 mg/mL (146.91 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||17.28 mL||86.42 mL||172.83 mL|
|0.5 mM||3.46 mL||17.28 mL||34.57 mL|
|1 mM||1.73 mL||8.64 mL||17.28 mL|
|5 mM||0.35 mL||1.73 mL||3.46 mL|
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2