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Neuraminidase-IN-12

Neuraminidase Inhibitor

Neuraminidase-IN-12 is a potent neuraminidase inhibitor, primarily targeting the viral neuraminidase enzyme to mitigate viral proliferation. This compound demonstrates significant antiviral activity against Newcastle disease virus (NDV) by effectively preventing the release of progeny virus particles from infected Vero cells. In addition to its antiviral properties, Neuraminidase-IN-12 features an azide group, making it suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions for various click chemistry applications, enhancing its utility in chemical biology research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2218480-15-8
Applications	Neuraminidase Inhibitor
Formula	C₁₁H₁₃F₃N₄O₇
Molecular Weight	370.24
SMILES	FC(F)(F)C(N[C@H]1[C@](OC(C(O)=O)=C[C@@H]1N=[N+]=[N-])([H])[C@H](O)[C@H](O)CO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.