Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent that targets MAO-B with an IC50 value of 10.30 μM. It demonstrates significant inhibition of Aβ1-42 aggregation, achieving 96.33% reduction at a concentration of 25 μM. Additionally, Neuroinflammatory-IN-2 provides neuroprotective effects in H2O2-induced PC-12 cell injury and exhibits biometal chelating and antioxidant properties. With favorable blood-brain barrier permeability, this compound is suitable for research applications related to Alzheimer’s disease and neuroinflammatory conditions.
Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent that targets MAO-B with an IC50 value of 10.30 μM. It demonstrates significant inhibition of Aβ1-42 aggregation, achieving 96.33% reduction at a concentration of 25 μM. Additionally, Neuroinflammatory-IN-2 provides neuroprotective effects in H2O2-induced PC-12 cell injury and exhibits biometal chelating and antioxidant properties. With favorable blood-brain barrier permeability, this compound is suitable for research applications related to Alzheimer’s disease and neuroinflammatory conditions.
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