NF-κB-IN-10 is a potent inhibitor of the NF-κB signaling pathway, primarily targeting NF-κB activation. This compound has demonstrated the ability to alleviate heart failure by mitigating oxidative stress and inflammation through the modulation of the Nrf2/NF-κB axis. In RAW264.7 cells, NF-κB-IN-10 effectively inhibits lipopolysaccharide-induced nitric oxide production, as well as the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). This reagent is invaluable for research into cardiovascular diseases and related inflammatory processes.
NF-κB-IN-10 is a potent inhibitor of the NF-κB signaling pathway, primarily targeting NF-κB activation. This compound has demonstrated the ability to alleviate heart failure by mitigating oxidative stress and inflammation through the modulation of the Nrf2/NF-κB axis. In RAW264.7 cells, NF-κB-IN-10 effectively inhibits lipopolysaccharide-induced nitric oxide production, as well as the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). This reagent is invaluable for research into cardiovascular diseases and related inflammatory processes.
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