Fig. 1 · Structure
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NGD 98-2
CRF-1 Receptor Antagonist
NGD 98-2 is an orally active corticotropin-releasing factor-1 (CRF-1) receptor antagonist. It demonstrates significant biological activity by modulating stress-related physiological responses, making it valuable for studies related to anxiety, depression, and stress disorders. This compound is useful in exploring the role of CRF-1 in various neurobiological pathways and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 355836-54-3 |
| Applications | CRF-1 Receptor Antagonist |
| Formula | C19H24F3N3O3 |
| Molecular Weight | 399.41 |
| SMILES | CC1=C(C2=CC=C(OC(F)(F)F)C=C2OC)N=C(OC)C(NC(CC)CC)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.