Fig. 1 · Structure
Documents & Downloads
NH-bis(PEG2-propargyl)
PROTAC linker
NH-bis(PEG2-propargyl) is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an alkyne moiety that enables the copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with azide-containing molecules. Its function as a versatile click chemistry reagent facilitates the development of targeted protein degradation strategies, making it valuable for research in targeted therapeutics and cellular signaling pathways.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2100306-83-8 |
| Applications | PROTAC linker |
| Formula | C14H23NO4 |
| Molecular Weight | 269.34 |
| SMILES | C#CCOCCOCCNCCOCCOCC#C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.