NH-bis(PEG2-propargyl)

Catalog No.: A82404
PROTAC linker
NH-bis(PEG2-propargyl) is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an alkyne moiety that enables the copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with azide-containing molecules. Its function as a versatile click chemistry reagent facilitates the development of targeted protein degradation strategies, making it valuable for research in targeted therapeutics and cellular signaling pathways.
Grouped product items
Size Price Stock Qty
5mg
$30.00
In stock
10mg
$45.00
In stock
100mg
$95.00
In stock
250mg
$140.00
In stock
500mg
$250.00
In stock
1g
$475.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNH-bis(PEG2-propargyl) is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an alkyne moiety that enables the copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with azide-containing molecules. Its function as a versatile click chemistry reagent facilitates the development of targeted protein degradation strategies, making it valuable for research in targeted therapeutics and cellular signaling pathways.
Product Information
Catalog NumA82404
FormulaC14H23NO4
Molecular Weight269.34
CAS Number2100306-83-8
SMILESC#CCOCCOCCNCCOCCOCC#C
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