NH2-C4-NH-Boc is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyl/ether structure, facilitating the connection of two distinct ligands: one targeting an E3 ubiquitin ligase and the other directed at the protein of interest. By harnessing the ubiquitin-proteasome system, PROTACs constructed with NH2-C4-NH-Boc enable selective degradation of specific target proteins, making it a valuable reagent for research in targeted protein degradation and drug development.
NH2-C4-NH-Boc is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyl/ether structure, facilitating the connection of two distinct ligands: one targeting an E3 ubiquitin ligase and the other directed at the protein of interest. By harnessing the ubiquitin-proteasome system, PROTACs constructed with NH2-C4-NH-Boc enable selective degradation of specific target proteins, making it a valuable reagent for research in targeted protein degradation and drug development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
