Fig. 1 · Structure
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NH2 DOTA-GA
Bifunctional Chelator
NH2 DOTA-GA is a bifunctional chelator based on the DOTA structure, designed for the preparation of radionuclide drug conjugates (RDCs). Its carboxylic acid groups facilitate the complexation of metal ions, such as Gd(III), making it a valuable tool in radiopharmaceutical development. NH2 DOTA-GA is suitable for applications in targeted imaging and therapy, enhancing the efficacy of radiolabeled agents in various biological research settings.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1639843-65-4 |
| Applications | Bifunctional Chelator |
| Formula | C21H38N6O9 |
| Molecular Weight | 518.56 |
| SMILES | O=C(NCCN)CCC(N1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.