NH2-PEG4-CH2CH2COOH

Catalog No.: A42602
ADC Linker
NH2-PEG4-CH2CH2COOH is a cleavable four-unit polyethylene glycol (PEG) linker designed for the synthesis of antibody-drug conjugates (ADCs) and PROTACs (proteolysis-targeting chimeras). This linker facilitates the conjugation of antibodies with cytotoxic agents, enhancing targeted drug delivery and therapeutic efficacy. Additionally, its application in PROTAC synthesis supports the development of innovative strategies for targeted protein degradation.
Grouped product items
Size Price Stock Qty
100mg
$25.00
In stock
500mg
$50.00
In stock
1g
$80.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNH2-PEG4-CH2CH2COOH is a cleavable four-unit polyethylene glycol (PEG) linker designed for the synthesis of antibody-drug conjugates (ADCs) and PROTACs (proteolysis-targeting chimeras). This linker facilitates the conjugation of antibodies with cytotoxic agents, enhancing targeted drug delivery and therapeutic efficacy. Additionally, its application in PROTAC synthesis supports the development of innovative strategies for targeted protein degradation.
Product Information
Catalog NumA42602
FormulaC11H23NO6
Molecular Weight265.30
CAS Number663921-15-1
SMILESO=C(O)CCOCCOCCOCCOCCN
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