Fig. 1 · Structure
Documents & Downloads
NH2-PEG5-C2-NH-Boc
PROTAC Linker
NH2-PEG5-C2-NH-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs, which are bifunctional molecules that target proteins for ubiquitination and subsequent degradation. This linker facilitates the conjugation of targeting ligands to E3 ligases, enhancing the efficacy of targeted protein degradation studies. NH2-PEG5-C2-NH-Boc is ideal for applications in chemical biology and therapeutic research, allowing for the precise modulation of protein levels within cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 189209-27-6 |
| Applications | PROTAC Linker |
| Formula | C17H36N2O7 |
| Molecular Weight | 380.48 |
| Synonyms | PROTAC Linker 17 |
| SMILES | O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.