NHPI-PEG2-C2-NHS ester

Catalog No.: A42914
ADC linker
NHPI-PEG2-C2-NHS ester is a non-cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This 2-unit PEG linker provides increased stability and solubility, facilitating the delivery of cytotoxic agents to targeted cells. Its application in ADC development enhances therapeutic efficacy and minimizes off-target effects, making it a valuable reagent for cancer research and drug formulation studies.
Grouped product items
Size Price Stock Qty
50mg
$230.00
In stock
100mg
$360.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNHPI-PEG2-C2-NHS ester is a non-cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This 2-unit PEG linker provides increased stability and solubility, facilitating the delivery of cytotoxic agents to targeted cells. Its application in ADC development enhances therapeutic efficacy and minimizes off-target effects, making it a valuable reagent for cancer research and drug formulation studies.
Product Information
Catalog NumA42914
FormulaC19H20N2O9
Molecular Weight420.37
CAS Number2101206-31-7
SMILESO=C(ON1C(CCC1=O)=O)CCOCCOCCON(C(C2=C3C=CC=C2)=O)C3=O
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