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NHPI-PEG3-C2-NHS ester

Catalog No.: A43302
ADC linker
NHPI-PEG3-C2-NHS ester is a non-cleavable three-unit polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This linker enhances the solubility and stability of ADCs while maintaining their potency. It is particularly useful for facilitating the targeted delivery of cytotoxic agents to cancer cells, making it a valuable tool in cancer research and development of therapeutic strategies.
NHPI-PEG3-C2-NHS ester 2101206-14-6 ADC linker
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNHPI-PEG3-C2-NHS ester is a non-cleavable three-unit polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This linker enhances the solubility and stability of ADCs while maintaining their potency. It is particularly useful for facilitating the targeted delivery of cytotoxic agents to cancer cells, making it a valuable tool in cancer research and development of therapeutic strategies.
Product Information
Catalog NumA43302
FormulaC21H24N2O10
Molecular Weight464.42
CAS Number2101206-14-6
SMILESO=C(ON1C(CCC1=O)=O)CCOCCOCCOCCON(C(C2=C3C=CC=C2)=O)C3=O
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Antibody-drug Conjugates (ADC) > ADC Linker