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Nicousamide

Name: Nicousamide
Brand: Adooq Bioscience
SKU: A84919
Availability: OutOfStock

Cat. No. A84919 CAS 704881-43-6

TGF-β Receptor Inhibitor

Nicousamide is a potent TGF-β receptor II inhibitor that effectively prevents phosphorylation of this receptor. This compound is instrumental in investigating renal fibrosis and its underlying mechanisms, particularly in animal models of diabetic nephropathy. Researchers can utilize Nicousamide to explore therapeutic strategies aimed at mitigating fibrotic processes in kidney disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	704881-43-6
Applications	TGF-β Receptor Inhibitor
Formula	C₁₈H₁₂N₂O₉
Molecular Weight	400.30
SMILES	O=C(C1=CC(NC(C2=CC3=CC([N+]([O-])=O)=C(C(C)=C3OC2=O)O)=O)=CC=C1O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.