Fig. 1 · Structure
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Nimustine
Anticancer Agent
Nimustine is an alkylating agent that induces DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), activating the DNA damage response (DDR) signaling pathway. By stimulating the p38 MAPK and JNK signaling pathways, Nimustine exhibits significant antitumor activity. This compound is utilized in cancer research for its potential to enhance apoptosis and impede tumor growth.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 42471-28-3 |
| Applications | Anticancer Agent |
| Formula | C9H13ClN6O2 |
| Molecular Weight | 272.69 |
| SMILES | O=C(NCC1=CN=C(C)N=C1N)N(CCCl)N=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.