Fig. 1 · Structure
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NK1 receptor antagonist 2
NK1 receptor Antagonist
NK1 receptor antagonist 2 acts as a selective antagonist for the neurokinin-1 (NK1) receptor, which plays a critical role in mediating pain and inflammatory responses. This compound demonstrates significant biological activity in reducing NK1 receptor signaling, making it relevant for research applications involving tinnitus and hearing loss. Its use may facilitate the exploration of therapeutic interventions targeting these auditory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 579475-17-5 |
| Applications | NK1 receptor Antagonist |
| Formula | C31H35F7N4O2 |
| Molecular Weight | 628.62 |
| SMILES | C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N(C)C(N2[C@](C3=C(C=C(C=C3)F)C)([H])C[C@@](N4C[C@@]5([H])N(C(CC5)=O)CC4)([H])CC2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.