Fig. 1 · Structure

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NLRP3 agonist 1

NLRP3 Agonist

NLRP3 Agonist 1 is a potent agonist targeting the NLRP3 inflammasome. This compound has been shown to activate Caspase-1, leading to the cleavage of pro-inflammatory cytokines pro-IL-1β and pro-IL-18 into their active forms. NLRP3 Agonist 1 can be utilized in research focused on inflammation and immune response pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2454019-69-1
Applications NLRP3 Agonist
Formula C15H16N6
Molecular Weight 280.33
SMILES
NC1=NC(NC2(C)CC2)=C3C(C=C(C=C3)C4=NNC=C4)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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