Fig. 1 · Structure
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NLRP3 antagonist 1
NLRP3 Antagonist
NLRP3 Antagonist 1 is a selective antagonist of the NLRP3 inflammasome, primarily expressed in macrophages and neutrophils. This compound plays a crucial role in modulating the innate immune response to pathogenic infections and cellular stress. NLRP3 Antagonist 1 has potential applications in cancer research and other inflammatory diseases, providing a valuable tool for studying the underlying mechanisms of NLRP3-mediated pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2454017-83-3 |
| Applications | NLRP3 Antagonist |
| Formula | C16H18N6O |
| Molecular Weight | 310.35 |
| SMILES | O[C@@H]1[C@H](NC2=C3C=CC(C4=NNC=C4)=CC3=NC(N)=N2)CCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.