Fig. 1 · Structure

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NLRP3-IN-26

NLRP3 Inhibitor

NLRP3-IN-26 is a specific inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 0.13 μM. This compound is useful for studying the role of NLRP3 in inflammatory processes and can be applied in models of DSS-induced colitis to elucidate its impact on intestinal inflammation and immune responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2927413-30-5
Applications NLRP3 Inhibitor
Formula C31H33ClN2O6S
Molecular Weight 597.12
SMILES
O=C(N(C1CC2=CC=C(S(=O)(NCCC)=O)C=C2C1)CC3=CC(Cl)=CC=C3OCCOC)C4=CC5=C(C=CC=C5)O4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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