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NLRP3-IN-31

NLRP3 Inhibitor

NLRP3-IN-31 is a selective inhibitor of the NLRP3 inflammasome, exhibiting an IC50 value in the range of 0.3-0.5 μM. This compound effectively modulates the activation of NLRP3, making it a valuable tool for studying inflammatory pathways. NLRP3-IN-31 can be utilized in research focused on autoinflammatory diseases, metabolic disorders, and neuroinflammation, aiding in the understanding of inflammasome-mediated processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2769040-08-4
Applications	NLRP3 Inhibitor
Formula	C₁₈H₁₇ClN₄O
Molecular Weight	340.81
SMILES	ClC1=CC=C(C2=C3C=CN=CC3=C(NCC4OCCC4)N=N2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.