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NLRP3-IN-38

NLRP3 Inhibitor

NLRP3-IN-38 is a selective inhibitor of the NOD-like receptor protein 3 (NLRP3), known for its role in mediating inflammatory responses through inflammasome activation. With an EC50 value of 23 nM, it effectively reduces the activation of the NLRP3 inflammasome, making it a valuable tool for research into inflammatory diseases. This compound is suited for studies evaluating the modulation of NLRP3-related signaling pathways and the development of therapeutic strategies targeting NLRP3-mediated inflammation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033054-46-2
Applications	NLRP3 Inhibitor
Formula	C₂₁H₂₁F₃N₄O₂
Molecular Weight	418.41
SMILES	C[C@H]1CN(C[C@H]([C@@H]1O)C)C2=C3C=NC=CC3=C(N=N2)C4=CC=C(C=C4O)C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.