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NLRP3-IN-4

NOD-like Receptor (NLR) Inhibitor

NLRP3-IN-4 is a potent inhibitor of the NOD-like receptor (NLR) NLRP3 inflammasome, exhibiting oral bioavailability. This compound is characterized by its ability to mitigate inflammatory processes, making it particularly relevant for research in inflammatory diseases such as colitis. It is a valuable tool for investigating the role of NLRP3 in immune responses and inflammation modulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2758595-77-4
Applications	NOD-like Receptor (NLR) Inhibitor
Formula	C₂₂H₂₂N₂O₅
Molecular Weight	394.42
SMILES	COC1=CC(OC)=CC(/C=C/C2=CC=C(C=C2)NC(C3CC3)=O)=C1/C=C/[N+]([O-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.