NLRP3-IN-44 is a selective inhibitor of the NLRP3 inflammasome, exhibiting potent activity with a Kd of 17.5 nM and approximately 62% oral bioavailability. This compound facilitates research into NLRP3-related pathologies by effectively modulating inflammasome activity. NLRP3-IN-44 is valuable for investigations into the roles of the NLRP3 inflammasome in inflammatory diseases.
NLRP3-IN-44 is a selective inhibitor of the NLRP3 inflammasome, exhibiting potent activity with a Kd of 17.5 nM and approximately 62% oral bioavailability. This compound facilitates research into NLRP3-related pathologies by effectively modulating inflammasome activity. NLRP3-IN-44 is valuable for investigations into the roles of the NLRP3 inflammasome in inflammatory diseases.
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