NLRP3-IN-61 is a potent inhibitor of NLRP3, targeting the NLRP3 inflammasome pathway. This compound effectively inhibits pyroptosis in THP-1 cells with an IC50 value of 12.6 nM and reduces IL-1β release with an IC50 of 25.3 nM. NLRP3-IN-61 is suitable for research applications investigating inflammatory responses and therapeutic interventions in diseases associated with the NLRP3 inflammasome.
NLRP3-IN-61 is a potent inhibitor of NLRP3, targeting the NLRP3 inflammasome pathway. This compound effectively inhibits pyroptosis in THP-1 cells with an IC50 value of 12.6 nM and reduces IL-1β release with an IC50 of 25.3 nM. NLRP3-IN-61 is suitable for research applications investigating inflammatory responses and therapeutic interventions in diseases associated with the NLRP3 inflammasome.
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