NLRP3-IN-65

Catalog No.: A35645
NLRP3 Inhibitor
NLRP3-IN-65 is a selective inhibitor of the NLRP3 inflammasome, a key component of the innate immune response. This compound exerts significant biological activity by inhibiting the activation of NLRP3, thereby modulating inflammatory responses. It is valuable for research applications related to autoinflammatory diseases, chronic inflammation, and potential therapeutic strategies aimed at controlling NLRP3-mediated pathways.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNLRP3-IN-65 is a selective inhibitor of the NLRP3 inflammasome, a key component of the innate immune response. This compound exerts significant biological activity by inhibiting the activation of NLRP3, thereby modulating inflammatory responses. It is valuable for research applications related to autoinflammatory diseases, chronic inflammation, and potential therapeutic strategies aimed at controlling NLRP3-mediated pathways.
Product Information
Catalog NumA35645
FormulaC20H24F3N3O
Molecular Weight379.42
CAS Number3052859-81-8
SMILESCC1=C(C2=CC=C(N=N2)C[C@H]3CN(CCC3)CC)C(O)=CC(C(F)(F)F)=C1
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