NLRP3-IN-70 is an inhibitor of the NLRP3 inflammasome, specifically designed to bind to the NACHT domain of the NLRP3 protein. By blocking the interaction between NLRP3 and ASC, it disrupts ASC oligomerization and subsequent inflammasome assembly. This compound is valuable for research into conditions such as sepsis and nonalcoholic steatohepatitis, providing insights into the regulation of inflammatory responses.
NLRP3-IN-70 is an inhibitor of the NLRP3 inflammasome, specifically designed to bind to the NACHT domain of the NLRP3 protein. By blocking the interaction between NLRP3 and ASC, it disrupts ASC oligomerization and subsequent inflammasome assembly. This compound is valuable for research into conditions such as sepsis and nonalcoholic steatohepatitis, providing insights into the regulation of inflammatory responses.
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