NLRP3-IN-79 is a potent, orally active inhibitor of the NLRP3 inflammasome, with an IC50 of 10.69 nM. It functions by directly binding to NLRP3, disrupting the NEK7-NLRP3 interaction and preventing inflammasome assembly. This compound is valuable for research into NLRP3-related diseases, such as systemic inflammation, peritonitis, and colitis, facilitating insights into therapeutic strategies targeting inflammasome-mediated pathways.
NLRP3-IN-79 is a potent, orally active inhibitor of the NLRP3 inflammasome, with an IC50 of 10.69 nM. It functions by directly binding to NLRP3, disrupting the NEK7-NLRP3 interaction and preventing inflammasome assembly. This compound is valuable for research into NLRP3-related diseases, such as systemic inflammation, peritonitis, and colitis, facilitating insights into therapeutic strategies targeting inflammasome-mediated pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
