Fig. 1 · Structure

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NLRP3 modulator 7

NLRP3 Modulator

NLRP3 Modulator 7 is a specific inhibitor of the NLRP3 inflammasome, effectively regulating its activity. This compound demonstrates potent inhibitory effects on interleukin-1 beta (IL-1β) secretion, with an IC50 value of less than 500 nM. NLRP3 Modulator 7 is applicable in research focused on inflammatory diseases and disorders related to the NLRP3 pathway.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2982797-42-0
Applications NLRP3 Modulator
Formula C19H22F3N3O2
Molecular Weight 381.39
SMILES
OC1=C(C2=C(C=C(N=N2)[C@@H]([C@@]3([H])CN(CCC3)C)O)C)C=CC(C(F)(F)F)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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