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NMDAR antagonist 5

Name: NMDAR antagonist 5
Brand: Adooq Bioscience
SKU: A67402
Availability: OutOfStock

Cat. No. A67402 CAS 3038464-68-2

NMDAR Antagonist

NMDAR antagonist 5 (Compound A17) is a selective antagonist targeting the N-methyl-D-aspartate receptor (NMDAR) with an IC50 of 0.3 µM. This compound also inhibits monoamine transporters, including the serotonin transporter (SERT, IC50 = 1.1 µM), dopamine transporter (DAT, IC50 = 0.7 µM), and norepinephrine transporter (NET, IC50 = 2.7 µM). With a favorable safety profile and low toxicity across multiple organ systems, NMDAR antagonist 5 demonstrates potential antidepressant effects, making it a valuable tool for research into depression and related neurological disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	3038464-68-2
Applications	NMDAR Antagonist
Formula	C₁₇H₂₁N₃
Molecular Weight	267.37
SMILES	C1([C@]2(N3CCCC3)CC(C=NN4)=C4CC2)=CC=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.