NMS-P945

Name: NMS-P945
Brand: Adooq Bioscience
SKU: A43290
Rating: 5 (288 reviews)

Catalog No.: A43290

ADC Linker

NMS-P945 is a reactive linker designed for the synthesis of antibody-drug conjugates (ADCs). It facilitates the conjugation to monoclonal antibodies (mAbs) with a reproducible Drug Antibody Ratio (DAR) exceeding 3.5. This compound enhances the efficacy and stability of ADCs, making it a valuable tool in targeted cancer therapy research applications.

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Research use only. We do not sell to patients.

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Biological Activity

Description	NMS-P945 is a reactive linker designed for the synthesis of antibody-drug conjugates (ADCs). It facilitates the conjugation to monoclonal antibodies (mAbs) with a reproducible Drug Antibody Ratio (DAR) exceeding 3.5. This compound enhances the efficacy and stability of ADCs, making it a valuable tool in targeted cancer therapy research applications.

Product Information

Catalog Num	A43290
Formula	C61H76ClN11O12S
Molecular Weight	1222.84
CAS Number	1466546-35-9
SMILES	O=C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N(C)CCN(C)C(OC(C3=C4C(C)=CS3)=CC5=C4[C@H](CCl)CN5C(C6=CC(C=C(C=C7)OCCN8CCCC8)=C7N6)=O)=O)=O)C=C2)=O)=O)=O)C=CC1=O

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