Fig. 1 · Structure
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Nocloprost
EP1/EP3 Receptor Agonist
Nocloprost is an orally active agonist of the EP1 and EP3 receptors, functioning as a prostaglandin E2 (PGE2) analog. This compound demonstrates significant biological activity by inhibiting evoked [3H]ACh release, showcasing its potential in neuroprotective research. Nocloprost exhibits gastroprotective and ulcer-healing properties, effectively accelerating the healing of chronic gastric ulcers and promoting mucosal growth in experimental models. As such, it serves as a valuable reagent for studying gastrointestinal health and related therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 79360-43-3 |
| Applications | EP1/EP3 Receptor Agonist |
| Formula | C22H37ClO4 |
| Molecular Weight | 400.98 |
| SMILES | CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H]([C@H](Cl)C[C@H]1O)C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.