Fig. 1 · Structure

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Nonylbenzene-PEG5-OH

PROTAC Linker

Nonylbenzene-PEG5-OH is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of proteolysis targeting chimeras (PROTACs). This compound facilitates the conjugation of targeting moieties to E3 ligase binding domains, enhancing the degradation of specific proteins through the ubiquitin-proteasome system. Its unique structure allows for improved solubility and stability in biological systems, making it an essential tool for researchers investigating targeted protein modulation and degradation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 20636-48-0
Applications PROTAC Linker
Formula C25H44O6
Molecular Weight 440.61
SMILES
OCCOCCOCCOCCOCCOC1=CC=C(CCCCCCCCC)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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