Fig. 1 · Structure
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Nonylbenzene-PEG8-OH
PROTAC Linker
Nonylbenzene-PEG8-OH is a PEG-based linker specifically designed for use in the synthesis of proteolysis targeting chimera (PROTAC) molecules. This compound facilitates the formation of stable and effective PROTACs by connecting the ligand and the E3 ligase components, enhancing target degradation. Its application in chemical research supports the development of targeted therapies and the exploration of protein modulation mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 41506-14-3 |
| Applications | PROTAC Linker |
| Formula | C31H56O9 |
| Molecular Weight | 572.77 |
| SMILES | OCCOCCOCCOCCOCCOCCOCCOCCOC1=CC=C(CCCCCCCCC)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.