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Norbornene-methyl-NHS

TCO Compound

Norbornene-methyl-NHS is a click chemistry reagent featuring a trans-cyclooctene (TCO) moiety, serving as a dienophile for conjugation through Diels-Alder reactions. This compound facilitates copper-free click reactions with tetrazines, enabling efficient and selective labeling of biomolecules. It is particularly useful in various research applications, including bioconjugation studies and the development of targeted therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1986791-87-0
Applications	TCO Compound
Formula	C₁₃H₁₅NO₅
Molecular Weight	265.26
SMILES	O=C(OCC1CC2C=CC1C2)ON3C(CCC3=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.