Fig. 1 · Structure
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(+)-Norfenfluramine hydrochloride
5-HT2B Receptor Agonist
(+)-Norfenfluramine hydrochloride is a selective agonist of the 5-HT2B receptor, exhibiting a Ki value of 11.2 nM. This compound effectively stimulates the hydrolysis of inositol phosphates and enhances intracellular calcium levels. Its biological activity makes it a valuable tool for studies related to primary pulmonary hypertension and valvular heart disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 37936-89-3 |
| Applications | 5-HT2B Receptor Agonist |
| Formula | C10H13ClF3N |
| Molecular Weight | 239.67 |
| Synonyms | d-Norfenfluramine hydrochloride |
| SMILES | N[C@@H](C)CC1=CC=CC(C(F)(F)F)=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.