Fig. 1 · Structure
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NOTA-bis(tBu)ester
PET Imaging Agent Precursor
NOTA-bis(tBu)ester serves as a precursor for PET imaging agents, specifically designed for radiolabeling with 68Ga. Upon conjugation with ZD2, it forms ZD2-(68Ga-NOTA), enabling targeted PET imaging studies of pancreatic cancer. This compound is vital for enhancing the visualization of tumor pathology and monitoring treatment response in preclinical and clinical research settings.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1161415-28-6 |
| Applications | PET Imaging Agent Precursor |
| Formula | C20H37N3O6 |
| Molecular Weight | 415.52 |
| Synonyms | NOTA-bis(t-Butyl ester) |
| SMILES | O=C(CN1CCN(CCN(CC1)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.