Fig. 1 · Structure

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NOTA trihydrochloride

BFC

NOTA trihydrochloride is a bifunctional chelator (BFC) that serves as a macrocyclic derivative of NOTA designed for tumor pre-targeting applications. This compound facilitates the conjugation of peptides and radionuclides, making it a valuable tool in cancer research and diagnostic imaging. Its ability to form stable complexes enhances its utility in various bioconjugation strategies, particularly in the development of targeted therapies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 133256-65-2
Applications BFC
Formula C12H24Cl3N3O6
Molecular Weight 412.69
SMILES
O=C(CN1CCN(CCN(CC1)CC(O)=O)CC(O)=O)O.Cl.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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