Fig. 1 · Structure

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NOTP

BFC

NOTP is a bifunctional chelator (BFC) and a macrocyclic derivative of NOTA, primarily utilized for tumor pre-targeting applications. Its unique structure allows for efficient conjugation with peptides and radionuclides, facilitating targeted delivery in cancer research. NOTP is instrumental in studies involving radiolabeled biomolecules for enhanced imaging and therapeutic strategies in oncology.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 83834-39-3
Applications BFC
Formula C9H24N3O9P3
Molecular Weight 411.22
SMILES
O=P(O)(CN(CCN(CP(O)(O)=O)CC1)CCN1CP(O)(O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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