Fig. 1 · Structure

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NPD4456

Vpr Inhibitor

NPD4456 is a 3-phenylcoumarin compound that functions as a Vpr inhibitor by competitively binding to the viral protein R (Vpr). This inhibition plays a critical role in blocking HIV-1 viral infection. NPD4456 is valuable for research focused on viral pathogenesis and the evaluation of new antiviral strategies targeting HIV.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 859668-98-7
Applications Vpr Inhibitor
Formula C21H21NO6
Molecular Weight 383.39
SMILES
O=C(OC1=CC=C(C(O2)=C1)C(C)=C(C3=CC(OC)=CC=C3OC)C2=O)N(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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