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Catalog No.: A16981

chloride channel blocker


NPPB Chemical Structure

CAS NO. 107254-86-4

NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist.

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Biological Activity

NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.3 mL 166.49 mL 332.99 mL
0.5 mM 6.66 mL 33.3 mL 66.6 mL
1 mM 3.33 mL 16.65 mL 33.3 mL
5 mM 0.67 mL 3.33 mL 6.66 mL

*The above data is based on the productmolecular weight 300.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16981
Actions Blocker
CAS No. 107254-86-4
Formula C16H16N2O4
M. Wt 300.31
Purity >98%
Synonyms HOE 144, Hoechst 144

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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