Catalog No.: A15929

hERG channel activator


NS-1643 Chemical Structure

CAS NO. 448895-37-2

NS-1643 is a Human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 uM).

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Biological Activity

NS-1643 is a Human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 uM).
In vitro DMSO 71 mg/mL (186.72 mM)
Water <1 mg/mL
Ethanol 71 mg/mL (186.72 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.3 mL 131.49 mL 262.98 mL
0.5 mM 5.26 mL 26.3 mL 52.6 mL
1 mM 2.63 mL 13.15 mL 26.3 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15929
Actions Activator
CAS No. 448895-37-2
Formula C15H10F6N2O3
M. Wt 380.25
Purity >98%
Synonyms NS 1643, NS1643

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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