NS-398

Catalog No.: A13116

COX-2 inhibitor‎

NS-398

NS-398 Chemical Structure

CAS NO. 123653-11-2

NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.

Availability: In stock

Package Price Qty
10 mg
$70.00
25 mg
$140.00
50 mg
$250.00
100 mg
$450.00
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Biological Activity

NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
Targets
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.81 mL 159.05 mL 318.11 mL
0.5 mM 6.36 mL 31.81 mL 63.62 mL
1 mM 3.18 mL 15.91 mL 31.81 mL
5 mM 0.64 mL 3.18 mL 6.36 mL

*The above data is based on the productmolecular weight 314.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13116
Actions Inhibitor
M. Wt 314.36
Formula C13H18N2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 123653-11-2
Synonyms NS398, NS 398
SMILES CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2

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