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NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.81 mL | 159.05 mL | 318.11 mL |
| 0.5 mM | 6.36 mL | 31.81 mL | 63.62 mL |
| 1 mM | 3.18 mL | 15.91 mL | 31.81 mL |
| 5 mM | 0.64 mL | 3.18 mL | 6.36 mL |
*The above data is based on the productmolecular weight 314.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13116 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 314.36 |
| Formula | C13H18N2O5S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 123653-11-2 |
| Synonyms | NS398, NS 398 |
| SMILES | CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2 |
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