NSC 13987 is a selective inhibitor of the HIV-1 Nef protein, specifically targeting site I. By binding to Nef, NSC 13987 disrupts its interaction with calnexin, leading to the restoration of cholesterol efflux that is typically inhibited by Nef. This compound is valuable for research into HIV-associated atherosclerosis, providing insights into the mechanisms behind HIV infection and its impact on lipid metabolism.
NSC 13987 is a selective inhibitor of the HIV-1 Nef protein, specifically targeting site I. By binding to Nef, NSC 13987 disrupts its interaction with calnexin, leading to the restoration of cholesterol efflux that is typically inhibited by Nef. This compound is valuable for research into HIV-associated atherosclerosis, providing insights into the mechanisms behind HIV infection and its impact on lipid metabolism.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
