NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy.
Product Information
Catalog Num
A17121
Formula
C11H9N3S
Molecular Weight
215.3
CAS Number
39122-38-8
SMILES
S=C(C1=NC=CC=C1)NC2=NC=CC=C2
Synonyms
NSC185058, NSC-185058
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
43 mg/mL (199.74 mM)
Water
Insoluble
Ethanol
21 mg/mL (97.55 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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