NSC 185058

Catalog No.: A17121

ATG4B antagonist

NSC 185058

NSC 185058 Chemical Structure

CAS NO. 39122-38-8

NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $160.00

Special Price $128.00

10 mg

Regular Price: $280.00

Special Price $224.00

50 mg

Regular Price: $980.00

Special Price $784.00

100 mg

Regular Price: $1,680.00

Special Price $1,344.00

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Biological Activity

NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy.
In vitro DMSO 43 mg/mL (199.74 mM)
Water Insoluble
Ethanol 21 mg/mL (97.55 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.45 mL 232.23 mL 464.47 mL
0.5 mM 9.29 mL 46.45 mL 92.89 mL
1 mM 4.64 mL 23.22 mL 46.45 mL
5 mM 0.93 mL 4.64 mL 9.29 mL

*The above data is based on the productmolecular weight 215.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17121
Actions Antagonist
CAS No. 39122-38-8
Formula C11H9N3S
M. Wt 215.3
Solubility DMSO
Purity >98%
Synonyms NSC185058, NSC-185058
SMILES S=C(C1=NC=CC=C1)NC2=NC=CC=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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