NSC 694623

Catalog No.: A29193
HAT Inhibitor
NSC 694623 is a potent inhibitor of histone acetyltransferases (HATs), with an IC50 value of 15.9 μM for recombinant p300/CBP-associated factor (PCAF). This compound exhibits antiproliferative effects on various cancer cell lines, making it a valuable tool for cancer research. Its capacity to modulate histone acetylation offers potential insights into epigenetic regulation and therapeutic strategies in oncology.
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
5mg
$80.00
In stock
10mg
$125.00
In stock
25mg
$250.00
In stock
50mg
$455.00
In stock
100mg
$625.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNSC 694623 is a potent inhibitor of histone acetyltransferases (HATs), with an IC50 value of 15.9 μM for recombinant p300/CBP-associated factor (PCAF). This compound exhibits antiproliferative effects on various cancer cell lines, making it a valuable tool for cancer research. Its capacity to modulate histone acetylation offers potential insights into epigenetic regulation and therapeutic strategies in oncology.
Product Information
Catalog NumA29193
FormulaC16H16N2OS
Molecular Weight284.38
CAS Number907957-34-0
SMILESO=C1N(C2=CC=C(CCCC)C=C2)SC3=NC=CC=C31
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