NSC16168

Catalog No.: A13260

ERCC1-XPF inhibitor

NSC16168

NSC16168 Chemical Structure

CAS NO. 6837-93-0

NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 μM. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer.

Availability: In stock

Package Price Qty
5 mg
$360.00
10 mg
$620.00
50 mg
$1,840.00
100 mg
$3,680.00
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Biological Activity

NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 μM. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.12 mL 105.6 mL 211.19 mL
0.5 mM 4.22 mL 21.12 mL 42.24 mL
1 mM 2.11 mL 10.56 mL 21.12 mL
5 mM 0.42 mL 2.11 mL 4.22 mL

*The above data is based on the productmolecular weight 473.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13260
Actions Inhibitor
CAS No. 6837-93-0
Formula C17H15NO9S3
M. Wt 473.5
Purity >98%
Synonyms NSC-6168, NS16168
SMILES NC1=C2C(C=C(S(=O)(O)=O)C=C2OS(C3=CC=C(C)C=C3)(=O)=O)=CC(S(O)(=O)=O)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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